The German Research Foundation (DFG) initiated a new Priority Program (SPP 1656) entitled “Intestinal Microbiota – a Microbial Ecosystem at the Edge between Immune Homeostasis and Inflammation” to establish an interdisciplinary network of scientists and infrastructures. The goal is to achieve a functional understanding of microbe-host interactions in health and diseases, beyond rapidly emerging knowledge of largely descriptive compositional and metagenomic analyses. This DFG Priority Program will support the German research community on this important topic over the next six years.
DFG Priority Programs support collaborative research networks based on thematically coherent and scientifically novel concepts. SPP 1656 includes 22 research groups from 17 different German institutions. The portfolio of knowledge within this research network covers a range of scientific disciplines including immunology, microbiology, gastroenterology, nutrition science and gnotobiology.
The gut provides an explicitly large and dynamic interface towards the luminal microbiota and tissue homeostasis is achieved by a compartimentalized immune system. Research projects of SPP 1656 are focused on microbe-host interactions related to the regulation of the mucosal immune system as well as infectious and chronic inflammatory disorders in the intestine.
Prof. Dr. Dirk Haller
Technische Universität München
NEW TEXTBOOK: The Gut Microbiome in Health and Disease
The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defensive systems.